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In this article we will discuss about the classification of bacteriophage.
1. Bacteriophages with DNA Genome:
A. Genome is double-stranded DNA, generally linear.
1. Family Myoviridae:
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Icosahedral, isometric or elongated head with a helical rigid tail containing a contractile sheath, tail plate, tail fibres and spikes.
Example: E. coli phage (coliphage) T2, T4, T6.
2. Family Styloviridae:
Icosahedral, isometric head with a long flexible tail without a contractile sheath. Tail fibres may or may not be present.
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Example: E. coli phage T1, T5.
3. Family Pedoviridae:
Icosahedral, isometric head with a sheath-less tail which is shorter than the head. Tail fibres may or may not be present.
Example: E. coli phage T3, T7.
4. Family Corticoviridae:
Icosahedral, isometric head without a tail. Capsid contains lipid in addition to protein. The genome is closed circular ds-DNA.
Example: Pseudomonas phage MP2.
5. Family Tectiviridae:
Icosahedral, isometric head without tail. Virion contains double capsid.
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Example: phage PRD 1.
6. Family Plasmaviridae:
Virion plemorphic, Enveloped.
Example Phage MV-L2.
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B. Genome single-stranded DNA:
1. Family Microviridae:
Icosahedral, isometric head without tail or envelope.
Example: E. coli phage φX174 having a circular ss-DNA genome.
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2. Family Inoviridae:
Helical symmetry; virions long rod shaped or filamentous; non-enveloped; genome circular ss-DNA.
Example: E. coli phage fd and bacteriophage MV-L1.
2. Bacteriophages with RNA Genome:
A. Genome double-stranded RNA
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1. Family Cystoviridae:
Capsid icosahedral, enveloped; ds-RNA is segmented; virions more or less spherical, about 90-100 nm in diameter.
Example: Phage φ6.
B. Genome single-stranded RNA
1. Family Leviviridae:
Capsid icosahedral, non-enveloped, ss-RNA is linear (+). Virions 26-27 nm in size.
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Example: Phages MS2 and Qβ.
Morphology of some representative bacteriophages is shown diagrammatically in Fig. 6.10: