Sulfonamides are synthetic chemotherapeutic agents. They were in common use as antimicrobial drugs prior to the advent of antibiotics. Frequent development of cross drug resistance in bacteria isolated from animals has now-a-days reduced their clinical values. Recently their use in combination with trimethoprim or orimethoprim is favoured on account of synergistic action and prevention of […]
Sulfonamides: Chemistry, Classification and Adverse Reactions | Animals
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Sulfa Drugs: Discovery, Structure and Effectiveness | Antibiotics
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In this article we will discuss about:- 1. Discovery of Sulfonamides 2. Structure of Sulfonamides 3. Mode of Action 4. Effectiveness. Discovery of Sulfonamides: The discovery of the sulfonamides or sulfa drugs in 1935 by Professor Gerhard Domagk (Fig. 45.1) and his team was a pioneering achievement in the war against infections, for which Domagk […]
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