In this article we will discuss about the production of pharmaceutical proteins in transgenic plants. Many pharmaceutical proteins of mammalian origin have been synthesized in plants. These ranges from blood products such as human serum albumin. There is an annual demand of more than 500 tonnes for many of these proteins. In view of their economic feasibility, transgenic plants have [...]
In this article we will discuss about the production of recombinant antibodies in transgenic plants. Antibodies are complex glycoproteins that recognise and bind to target antigen with high specificity (Fig. 16.2 or Fig. 16.3). Antibody production is restricted only to animals (mammals). Antibodies are used in diagnosis, prevention and treatment of disease. The productions of antibodies in plants are popularly [...]
In this article we will discuss about the genetic approach of molecular farming. One of the key objectives in molecular farming is the production of recombinant proteins at high yields. To accomplish high yield, expression construct must optimise every stages of gene expression, i.e., from transcription to protein stability. For high-level transcription, promoter and poly adenylation site, which are often [...]