This article provides a note on the antiseptics and disinfectants. History: Use of antiseptics and disinfectants evolved from the ancient Egyptian process of embalming. The Egyptian and other ancient people used various concoctions such as volatile oil, wines, vinegars, honey, balsam etc. as embalming. Persian required water to be stored in bright copper vessels. Salting, smoking and spicing the foods [...]
This article provides a note on anti cancerous drugs. Definition: Neo (Greek) mean new or plus and plasm mean growth. Neoplasm represents a pathologic over growth of tissue formed as a result of abnormal excessive, uncoordinated, autonomous and purposeless proliferation of cells which competes for metabolic substances with normal cells. Anti cancer drugs are agents that are used to kill/modify [...]
This article provides a note on the antimetabolites, explained with the help of suitable diagrams. Folate: MOA By structure folate consists of a pteridine nucleus. PABA and glutamic acid. These folates are taken up into cell actively and converted in presence of DHFR from FH2 into FH4. FH4 acts as a cofactor in the transfer of single carbon fragment via [...]