Here is a list of various macrolide antibiotics. 1. Erythromycin: (i) This macrolide antibiotic was isolated from Streptomyces erythreus, a soil- born organism in 1952. (ii) It consists of two sugars, desosamine and cladinose, which are attached to erythronolide, a macro cyclic lactone. (iii) It is slightly water soluble. (iv) The antibiotic remains more active, in alkaline medium than at [...]
After reading this article you will learn about the drugs used against protozoal diseases. Drug Used Against Trypanosomiasis: Diamidines: It has found to have trypanocidal activity due to the guanyl organic group NH: C(NH2) The presence of two guanyl organic group and separated by a paraffin hydrocarbon chain is found to give a high trypanocidal effect. As the length of [...]
This article throws light upon the three main drugs acting against heart worms. They are: 1. Thiacetarsamide Sodium 2. Dithiazanine 3. Diethylcarbamazine Citrate. Drug # 1. Thiacetarsamide Sodium: It consists of the sodium salt of S, S-diester of p-carbamolydithiobenzene aronous acid with mercaptoacetic acid. The chemical structure is depicted in Fig. 35.5. Therapeutic Effectiveness: After 4 doses of thiacetarsamide adult [...]