This article throws light upon the eight main physiological factors that affect the rate of drug absorption. The factors are: 1. Passage of Drug Molecule Across Membranes 2. pKa 3. pH – pka Partion Concept 4. pH-Partition Hypothesis 5. Active Transport 6. Facilitated Diffusion 7. Pinocytosis (Vesicular Transport) 8. Pore or Convective Transport. Physiologic Factor […]
Physiological Factors and Drug Absorption | Pharmacokinetics
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Metabolism of Drugs | Pharmacokinetics
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After reading this article you will learn about: 1. Definition and Need of Metabolism 2. Types of Metabolism. Definition and Need of Metabolism: Metabolism is a process of alteration of drugs in the body so as to modify their activity and structure. If lipophylic drugs are not metabolized it will be reabsorbed by the kidney […]
Pharmacokinetic Models: Concept and Types
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After reading this article you will learn about the concept and types of pharmacokinetic models. Concept of Pharmacokinetic Models: Drugs remain in dynamic state within the body and drug events often happen simultaneously. In order to describe a complex biologic system, assumptions are made concerning the movement of drugs. The mathematical models are used to […]
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