The following points highlight the eight main criticisms for Lyon’s hypothesis. Criticism # 1. That XO, XXX, XY, XX etc. individual differ among themselves suggesting that the entire X chromosome is not genetically inactive. If it were so, an XX and XXX female would have had no difference at all. From various chemical stigmata it seems that a part of [...]
The three examples of autosome-linked genetic disease are: 1. Sickle Cell Anemia 2. Alkaptonuria (Black Urine Disease) 3. Phenylketonuria. Example # 1. Sickle Cell Anemia: Sickle cell anemia is an inherited abnormal disease caused by mutation of autosomal gene. The red blood cells of certain individuals have peculiar property of undergoing reversible alterations in shape when subjected to changes in [...]
Two types of mutagens are considered here which are mostly affected the humans producing different mutations resulting in a number of abnormalities: 1. Radiation Exposure 2. Chemical Mutagenesis. Type # 1. Radiation Exposure: High energy radiation or ionising radiation produces a genetic alteration or mutation at a very low dose also. It has been shown experimentally that a low dose [...]