In this article we will discuss about:- 1. Definition of Down's Syndrome 2. Physical and Physiological Features of Down's Syndrome 3. Chromosomal Findings 4. Incidence 5. Causes. Definition of Down's Syndrome: The first autosomal abnormality described in man by John Langdon Down (1966) was known as Down's syndrome, more commonly used as mongolism. In this case, there is simple trisomy [...]
In this article we will discuss about the diversity of retroviral oncogenes. Studies of other retroviruses of several different animal species (most notably the mouse, rat, chicken, and certain species of monkeys) soon led to the identification of other retroviral oncogenes. Over 20 different retroviral oncogene (Table 16.2) have been described to date, and more undoubtedly remain to be discovered. [...]
In this article we will discuss about the examples of pedigree pattern of autosomal and sex chromosomal genetic diseases. 1. Pedigree pattern of an autosomal dominant trait. Note the vertical pattern of inheritance. Solid squares and circles indicating the affected males and females while hollow squares and circles are unaffected males and females. 2. Pedigree patterns of an autosomal recessive [...]