In this article we will discuss about the concept and units of genes. Concept of Gene: Although the role of hereditary units (factors) in transfer of genetic characters over several generations in organisms was advocated by Gregor John Mendel, yet the mystery of the ‘hereditary units’ was un-ravelled during early 1900s. In 1909, W. Johanson […]
Gene: Concept and Units (With Diagram) | Microbiology
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Cloning of Gene in Eukaryotes | Genetics
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Some procedures applied for gene cloning in eukaryotes are described in this context: 1. Transformation of Filamentous Fungi 2. Gene Transfer through Ti-plasmid of Agrobacterium 3. Gene Transfer through Gene Gun 4. Gene Bank or Genomic Library. 1. Transformation of Filamentous Fungi: Like bacteria, transformation of filamentous fungi has also been demonstrated. Hinnen (1978) first […]
Organisation of Immunoglobulin Genes | Microbiology
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In this article we will discuss about the organisation of immunoglobulin genes with special reference to multi-gene organisation. It has become clear that the B-lymphocytes of the immune system produce antibodies in the presence of antigen. The antibodies are formed from the assembly of some protein chains. In mammals, enormous amount of antibodies are produced. […]
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