This article throws light upon the three main types of pharmacokinetic variables of drugs. The variables are: 1. Plasma Half-Life (t1/2β) 2. Volumes of Distribution 3. Total Body Clearance (CIB). Type # 1. Plasma Half-Life (t1/2β): Half-life is defined as the time of declining the initial plasma drug concentration by half. It is also known […]
Types of Pharmacokinetic Variables | Drugs
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Expressing Percentage Concentration in a Drug: 3 Ways
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This article throws light upon the three main ways for expressing percentage concentration in a drug. The ways are: 1. Weight in Weight (W/W) 2. Weight in Volume (W/V) 3. Volume in Volume (V/V). Way # 1. Weight in Weight (W/W): This expression is used when solids are mixed with solids e.g. in powders, paste, […]
Factors Modifying Drug Effect and Dosage | Pharmacodynamics
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This article throws light upon the five major factors modifying drug effect and dosage. The factors are: 1. Physiological Factors 2. Genetic Factors 3. Pathological Factors 4. Environmental Factors 5. Therapeutic Factors. Factor # 1. Physiological Factors: i. Species: Absolute dose of a drug varies with species as different species are of different sizes, and […]
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