The following points highlight the four methods to detect and isolate mutants. The methods are: 1. Replica Plating Technique 2. Resistance Selection Method 3. Substrate Utilization Method 4. Carcinogenicity Test. 1. Replica Plating Technique: Lederberg and Lederberg (1952) have given replica plating technique. This technique is used to detect auxotrophic mutants which differentiates between mutants […]
4 Methods to Detect and Isolate Mutants | Genetics
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