In this article we will discuss about the molecular structure of centromere. Eukaryotic chromosomes possess a segregational device called centromere which is responsible for the chromosomc movement during cell division. Chromosome fragments without a centromere (acentric fragments) are unable to move to any of the poles during cell division; as a result, they are excluded from the daughter nuclei and [...]
In this article we will discuss about:- 1. Meaning of Deficiency in Chromosome 2. Origin of Deficiency in Chromosomes 3. Deletion in Human 4. Chromosome Pairing 5. Uses. Meaning of Deficiency in Chromosome: The term deficiency was coined by Bridges in 1917. It may be defined as a structural change resulting in the loss of a terminal acentric chromosome, chromatid [...]
In this article we will discuss about the structure and synthesis of telomere. Structure of Telomere: Molecular genetic studies have shown that the telomere consists of several short sequences which are tandemly repeated (Table 8.8). The general formula for the composition of the repeating units in one strand of the telomeres of all the eukaryotes is as follows: 5' Cn [...]