The below mentioned article provides a short note on DNA repair synthesis. Several types of damages, such as breakage in DNA strand, alteration of base pairs, cross linking of DNA with DNA or cross linking of DNA with proteins and pyrimidine dimer formation etc., may occur in chromosomes. These damages may be caused by mutagens produced within the cell itself [...]
In this article we will discuss about:- 1. Subject-Matter of Replication and Synthesis of Nucleic Acids 2. Unidirectional and Bidirectional Replications of Nucleic Acids 3. Enzymes and Proteins Involved in DNA Replication and Repair 4. Replication of Double-Stranded Circular DNA 5. RNA Primer Synthesis 6. Leading Strand and Lagging Strand and Other Details. Contents: Subject-Matter of Replication and Synthesis of Nucleic [...]
In this article we will discuss about the molecular structure of centromere. Eukaryotic chromosomes possess a segregational device called centromere which is responsible for the chromosomc movement during cell division. Chromosome fragments without a centromere (acentric fragments) are unable to move to any of the poles during cell division; as a result, they are excluded from the daughter nuclei and [...]