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The upcoming discussion will update you about the differences between replication and transcription.
Replication:
1. Occurs in the S phase of cell cycle.
2. Catalyzed by DNA polymerase enzymes.
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3. Deoxyribonucleoside triphosphates (dATP, dGTP, dCTP, dTTP) serve as raw materials.
4. Takes place along both the strands of DNA.
5. Involves unwinding and splitting of the entire DNA molecule (chromosome).
6. Involves copying of the entire genome.
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7. Replicated DNA strand remains hydrogen- bonded to its template DNA strand.
8. Two double-stranded DNA molecules are formed from one DNA molecule.
9. Products remain within the nucleus.
10. Products are not degraded
Transcription:
1. Occurs in the G1 and G2 phases of cell cycle.
2. Catalyzed by RNA polymerase enzymes.
3. Ribonucleoside triphosphates (ATP, GTP, CTP, and UTP) serve as raw materials.
4. Takes place along one strand of DNA.
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5. Involves unwinding and splitting of only those genes which are to be transcribed.
6. Involves copying of certain individual genes only.
7. Transcribed RNA strand separates from its DNA template strand.
8. A single one-stranded RNA molecule is formed from a segment of one DNA strand.
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9. Greater part of the products passes from the nucleus into the cytoplasm.
10. Products are degraded after their function is over.
