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The upcoming discussion will update you about the difference between DNA and RNA .
Difference # DNA:
1. They are formed by 4 types of monomeric units such as adenylate, guanylate, cytidylate and thymidylate.
2. The sugar moiety is deoxyribose.
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3. They are present in nucleus, probably in the chromosomes.
4. They carry “genetic Information” from one generation of cells to the next and undergo mutation.
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5. They contain 1,600 to 9,000 nucleotides. The molecules are long and thread-like having a length of about 250 times greater than their breadth. Their structure is highly complex.
6. They are concerned with protein synthesis.
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7. They have 2 strands of antiparallel double helical structure.
8. Heat, acid and alkali denature DNA molecules.
9. They have ‘sense’ and ‘antisense’ strands.
Difference # RNA:
1. They are also formed by 4 types of monomeric units such as adenylate, guanylate, cytidylate, uracidylate.
2. The sugar moiety is D-ribose.
3. They are present in cytoplasm and nucleolus.
4. They carry no “genetic information” and undergo no mutation.
5. They contain 60 to 6,000 nucleotides. The molecules are un-branched. Their structure is less rigid.
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6. They are also concerned with protein synthesis.
7. They exit as a single-stranded molecule.
8. The alkali hydrolysis is useful diagnostically and analytically.
9. The sequence of RNA molecule is the same as that of the ‘antisense’ strand of DNA.
